Season 4
Episode Guide
PLAIN SLICE
S4
E1
Mar 11, 2022
Desus & Mero go in on the week. Guest: Denzel Washington. Season premiere.
IT'S GONNA HIT
S4
E2
Mar 25, 2022
Desus & Mero hit the week's stories. Guests: Tom Holland, Mark Wahlberg.
GRAB YOUR BAGS
S4
E3
Apr 1, 2022
Desus & Mero cover the week's news and culture. Guest: Samuel L. Jackson.
BIG HATER ENERGY
S4
E5
Apr 15, 2022
Desus & Mero cover the week's news and culture. Guest: Michelle Yeoh.
LUCITE SITUATION
S4
E6
Apr 22, 2022
Desus & Mero cover the week's news and culture. Guest: Damson Idris.
CHEATER BELLY
S4
E7
Apr 29, 2022
Desus & Mero cover the week's news and culture. Guest: Earl Sweatshirt.
RUM ON THEIR GUMS
S4
E9
May 13, 2022
Desus & Mero cover the week's news and culture. Guest: Janelle James.
IT'S A PARTY NOW
S4
E10
May 20, 2022
Desus & Mero cover the week's news and culture. Guest: Quinta Brunson.
BOTTLES, BOTTLES, BOTTLES
S4
E11
May 27, 2022
Desus & Mero cover the week's news and culture. Guest: Kenan Thompson.
SAY NO TO THE MUSTACHE
S4
E13
Jun 10, 2022
Desus & Mero cover the week's news and culture. Guest: Wanda Sykes.
SCIENCE AND FELONIES
S4
E14
Jun 17, 2022
Desus & Mero cover the week's news and culture. Guest: Seth Meyers.